Oprah Winfrey, Julia Roberts, Common, Mandy Moore, Jennifer Garner and Yo-Yo Ma are among those set to participate, as will former President George W. Bush.
The event is being called a celebration of “our shared humanity,” according to a press release.
It begins May 1 at 8 p.m. ET and will run until the same time on May 2.
Over 200 “cultural, spiritual, civic, and community leaders” are set to participate, the release said.